Ion channels are important drug targets because they play a crucial role in controlling a very wide spectrum of physiological processes, and also ion channels are closely related to drug safety. WuXi Biology has been providing ion channel services for over 10 years. We now WuXi offers a broad portfolio of functional assessments on ion channel at various drug discovery stages to accelerate your new drug discovery progress.
Ion Channel Expression System Generation
Ion channel stable cell line generation
Ion channel BacMam expression system construction
Cardiac Safety Services
hERG and other cardiac channel testing: ion channel cardiac safety panel (CIPA compliant)
Stem cell derived cardiomyocyte studies with MEA
Click here for more information about the cardiac safety services.
Ion Channel Drug Discovery Services
Compound screening: Ion channel HTS, support to lead optimization programmes
MOA studies for lead compounds: Conventional patch-clamp studies at cellular or tissue level, using stable cell lines expressing ion channels, native cells (dissociated DRG cells, primary cultured cortical or hippocampal neurons) and/or IPSC derived neurons or cardiomyocytes
Automated patch-clamp: QPatch HTX, IonWorks Quattro