CN
High Content Platform

Overview

Cell-based functional bioassays of bio-relevant activities of enzymes, receptors, and signaling molecules and pathways.
Integrated multi-parameter analysis for customized specific needs.
 

Applications

  • Targeted Drug Screening
  • Target-Hit Search
  • Hit to Lead Identification
  • Lead Optimization
  • Drug Mechanism of Actions
  • Drug Kinetics
  • Drug Cytotoxicity
 

Specific Assays: 2D/3D/4D Image Based Quantitative and Semi-Quantitative Functional Bioassays

  • Cell Proliferation Assay (growth rate, doubling time, viability, etc.)
  • Cell Death Assay (apoptosis, necrosis, autophagy)
  • Cell Cycle Assay (cell cycle phases, mitosis, quiescence, senescence)
  • Subcellular Localization & Translocation Assay (endocytosis, exocytosis, nuclear/cytosol, nuclear structure)
  • Subcellular Organelle Function Assay (mitochondria, Golgi body, endoplasmic reticulum, etc.)
  • Membrane Integrity and Function Analysis
  • Kinase and Signal Transduction Analysis
  • Cell-Cell Interaction Analysis
  • Cell Sub-Population Analysis and Enrichment
  • Cytoskeleton and Extracellular Matrix Analysis
  • Cell Motility, Invasion, and Chemotaxis Assay
  • Oxidative Stress and Cellular Response Analysis
  • DNA and Chromosome Damage, and Genetic Instability Analysis
  • Epigenetic Modification Analysis
  • Transcription Activation and Gene Expression Analysis
  • DNA/Protein Synthesis and Degradation Analysis
  • Protein-Protein, Protein-DNA, Protein-RNA Interaction Analysis
  • Protein Post-Translational Modification and Activation Analysis
  • Customized Services - Please contact us for your special needs.